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Anti-Otx1 + Otx2 antibody
Anti-Otx1 + Otx2 antibody from Abcam
Be the first to write a review!
Citations:
(67)
Supplier Page
Supplier Page from
Abcam for
Anti-Otx1 + Otx2 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-Otx1 + Otx2 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Supplier Product Page
Catalog Number
ab21990
Antibody Type
Primary
Isotype
IgG
Quantity
100 UG
Applications
Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western blot
Clonality
Polyclonal
Host
Rabbit
Conjugate/Tag
Unconjugated
Gene Name
Otx2
Reactivity
Human, Mouse, Recombinant fragment
Target
Otx1 + Otx2
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (67)
(1)
Cell-type expression and activation by light of neuropsins in the developing and mature Xenopus retina
Frontiers in Cellular Neuroscience
September 20, 2023
Lawrence L. H. Man, Samuel S. Storey, Gabriel E. Bertolesi, Sarah McFarlane
immunohistochemistry
was performed by incubating the slides with antibodies for Otx2 (rabbit polyclonal
1:200
;
ab21990
,
Abcam
), Pax6 (rabbit polyclonal
1:100
, Cedarlane), Rhodopsin (
clone
4D2;
mouse
1:200
; Millipore) or
(2)
Multimodal characterization of murine gastruloid development
Cell Stem Cell
June 1, 2023
Simon Suppinger, Marietta Zinner, Nadim Aizarani, Ilya Lukonin, Raphael Ortiz, Chiara Azzi, Michael B. Stadler, Stefano Vianello, Giovanni Palla, Hubertus Kohler,
et al.
trajectory)",
BD Biosciences
,Cat #
611203
; RRID: AB_398737 Rabbit polyclonal anti-Otx1/2,
Abcam
,Cat #
ab21990
; RRID: AB_776930
Goat
polyclonal anti-Otx2,RnD,Cat# AF1979; RRID:AB_2157172 "
Mouse
monoclonal
anti-p44/42 MAPK (Erk1/2
(3)
The pluripotency factor Tex10 finetunes Wnt signaling for PGC and male germline development
bioRxiv
February 28, 2023
Dan Li, Jihong Yang, Fanglin Ma, Vikas Malik, Ruge Zang, Xianle Shi, Xin Huang, Hongwei Zhou, Jianlong Wang
anti-β-actin (
1:1000
, mouse IgG,
Sigma-Aldrich
,
clone
AC-15,
A5441
). anti-Otx2 (
1:1000
, rabbit IgG,
Abcam
,
ab21990
), anti-
Prdm1
(
1:1,000
, mouse IgG, Sigma-Aldrich,
clone
5E7, SAB5300402),
anti-Tex10
(
1:1000
, rabbit
(4)
The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration
PLOS Biology
January 17, 2023
Mazal Cohen-Gulkar, Ahuvit David, Naama Messika-Gold, Mai Eshel, Shai Ovadia, Nitay Zuk-Bar, Maria Idelson, Yamit Cohen-Tayar, Benjamin Reubinoff, Tamar Ziv,
et al.
immunoprecipitated
with 5 μg of goat anti-LHX2 antibody (
Millipore
,
ABE1402
) or OTX2 antibody (
Abcam
,
ab21990
).
ChIP-seq
libraries were prepared in duplicates and sequenced using G-INCPM in-house protocol. For
(5)
Failure of human rhombic lip differentiation underlies medulloblastoma formation
Nature
September 29, 2022
Liam D. Hendrikse, Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H. Sjoboen, Anders W. Erickson, Winnie Ong, Victor Gordon, Ludivine Coudière-Morrison, Audrey L. Mercier,
et al.
biological replicates for each cell line and silencing was confirmed
by western blot
(OTX2,
Abcam
,
ab21990
, rabbit, at
1:500
, and β-actin,
Sigma-Aldrich
,
A2228
,
mouse
, at 1/1000 was used as a loading control)
(6)
An Isogenic Collection of Pluripotent Stem Cell Lines With Elevated α-Synuclein Expression Validated for Neural Induction and Cortical Neuron Differentiation
Frontiers in Cell and Developmental Biology
May 30, 2022
Ammar Natalwala, Ranya Behbehani, Ratsuda Yapom, Tilo Kunath
mouse IgG1, DSHB ab528427), TBR1 (
1:200
, rabbit IgG,
Abcam
ab31940
), OTX1/2 (
1:1,000
, rabbit IgG,
Abcam
ab21990
), vimentin (2 μg/ml final, mouse IgM, DSHB 40E-C), and total αSyn (
1:1,000
, mouse IgG1,
BD
610787
).
(7)
OTX2 Homeoprotein Functions in Adult Choroid Plexus
International Journal of Molecular Sciences
August 19, 2021
Anabelle Planques et al.
supernatant was recovered and divided in two. Each half was incubated with 44 µg of either anti-OTX2 (
ab21990
,
Abcam
, Paris, France) or anti-IgG (
ab27478
,
Abcam
, Paris, France) antibodies coupled to magnetic beads
(8)
Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states
Scientific reports
July 15, 2021
Chen X, Emerson MM.
1:100
),
sheep
anti-Vsx2 (x1180p, Ex Alpha,
1:200
),
goat
anti-Otx2 (AF1979, R&D,
1:500
), rabbit anti-Otx2 (
AB21990
,
Abcam
,
1:500
) and rabbit anti-Olig2 (4B9610-AF488, Millipore,
1:500
). Sections were washed 3 times
(9)
Automating Human Induced Pluripotent Stem Cell Culture and Differentiation of iPSC-Derived Retinal Pigment Epithelium for Personalized Drug Testing
SLAS technology
June 1, 2021
Truong V, Viken K, Geng Z, Barkan S, Johnson B, Ebeling MC, Montezuma SR, Ferrington DA, Dutton JR.
AF1997
), OCT4 (
1:500
, Millipore Sigma MAB4401MI), PMEL17 (
1:200
,
DAKO
M063429–2
), OTX2 (
1:250
,
Abcam
ab21990
),
ZO1
(
1:500
,
Invitrogen
61–7300
). Secondary antibodies used were Alexa Fluor 488
Donkey
anti-Mouse
(10)
IFI16 promotes human embryonic stem cell trilineage specification through interaction with p53
npj Regenerative Medicine
December 1, 2020
Qian He, Zubiao Wu, Wei Yang, Doukou Jiang, Chaofeng Hu, Xiaofei Yang, Ning Li, Furong Li
was purchased from
Abcam
(
ab20680
,
Western blots
/
Immunofluorescence
), OTX2 was purchased from
Abcam
(
ab21990
,
Western blots
/
Immunofluorescence
), PAX6 was purchased from
Abcam
(
ab5790
,
Western blots
/
Immunofluorescence
),
(11)
Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice
Investigative ophthalmology & visual science
October 1, 2020
Landowski M, Grindel S, Shahi PK, Johnson A, Western D, Race A, Shi F, Benson J, Gao M, Santoirre E,
et al
.
beta-catenin (#
C2206
;
Sigma Aldrich
) to image
tight junctions
and RPE65 (#
ab13826
;
Abcam
), OTX1/OTX2 (#
ab21990
;
Abcam
), and
CRALBP
(#
ab15051
; Abcam) as RPE markers. RPE cells were stained with MitoTracker Red CMXRos
(12)
Generation of bicistronic reporter knockin mice for visualizing germ layers
Experimental Animals
November 6, 2019
Hayate Suzuki, Tra Thi Huong Dinh, Yoko Daitoku, Yoko Tanimoto, Kanako Kato, Takuya Azami, Masatsugu Ema, Kazuya Murata, Seiya Mizuno, Fumihiro Sugiyama
goat IgG (
1:300
,
AF1924
;
R&D Systems
, Minneapolis, MN, USA), anti-Otx2 polyclonal rabbit IgG (
1:200
;
ab21990
;
Abcam
, Cambridge, UK), or anti-Brachyury polyclonal goat IgG (
1:200
;
AF2085
,
R&D Systems
). After washing
(13)
Lineage tracing analysis of cone photoreceptor associated cis-regulatory elements in the developing chicken retina
Scientific reports
June 27, 2019
Schick E, McCaffery SD, Keblish EE, Thakurdin C, Emerson MM.
anti-Ap2α (3B5, DSHB,
1:200
) mouse IgG1 anti-Brn3a (
MAB1585
,
EMD Millipore
,
1:800
), and rabbit anti-Otx2 (
AB21990
,
Abcam
,
1:500
). All secondary antibodies were obtained from Jackson Immunoresearch and were appropriate
(14)
OTX2 Signals from the Choroid Plexus to Regulate Adult Neurogenesis
eneuro
April 22, 2019
Anabelle Planques, Vanessa Oliveira Moreira, Chantal Dubreuil, Alain Prochiantz, Ariel A. Di Nardo
low-bind tubes after
centrifugation
for 10 min at 16,000 × g. Antibody was added [2.5 µg of anti-OTX2 (
ab21990
,
Abcam
) or anti-IgG (
ab27478
,
Abcam
)] and incubated overnight at 4°C with rotation.
Protein A Sepharose
(15)
Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms
BMC developmental biology
March 7, 2019
Goto-Silva L, Ayad NME, Herzog IL, Silva NP, Lamien B, Orlande HRB, da Costa Souza A, Ribeiro S, Martins M, Domont GB,
et al
.
anti-FOXG1 (
ab18259
,
1:1000
;
Abcam
, UK), rabbit
anti-islet-1
(
ab20670
;
1:1000
;
Abcam
), rabbit anti–OTX-2 (
ab21990
,
1:200
;
Abcam
),
mouse
anti-glycogen synthetase (610,518,
1:500
; BD), and rabbit anti-PH3 (
06–570
,
1:500
;
(16)
Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
Stem cell reports
March 5, 2019
Kim H, Park HJ, Choi H, Chang Y, Park H, Shin J, Kim J, Lengner CJ, Lee YK, Kim J.
immunostained according to standard protocols using the following primary antibodies: OTX2 (
Abcam
,
AB21990
),
FOXA2
(
Abcam
,
AB108422
), NGN2 (
Millipore
,
AB5682
),
MASH1
(
BD Biosciences
,
556604
), TUJ1 (
Sigma
,
T2200
),
(17)
Contribution of noncoding pathogenic variants to RPGRIP1-mediated inherited retinal degeneration
Genetics in Medicine
March 1, 2019
Farzad Jamshidi et al.
H3K27ac (
Abcam
AB4729
, lot GF150367–1; RRID AB_2118291); CRX (Santa Cruz, B11X, lot E1409); OTX2 (
Abcam
,
AB21990
, lot GR242019–1);
NRL
(
Abcam
,
AB137193
, lot GR104520–2); RORB (Diagenode, pAb-001–100, lot HS-0010);
(18)
Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision
Scientific reports
February 19, 2019
Aldunate EZ, Di Foggia V, Di Marco F, Hervas LA, Ribeiro JC, Holder DL, Patel A, Jannini TB, Thompson DA, Martinez-Barbera JP,
et al
.
1:400
) for horizontal cells71, PAX6 (Covane PRB278P,
1:300
) for inner retinal cells72, OTX2 (
Abcam
AB21990
,
1:100
) for photoreceptor progenitors26, LM OPSIN (
Chemicon
AB5405
,
1:500
) for adult cones65, Cleave
(19)
Generation and Characterization of Induced Pluripotent Stem Cells and Retinal Organoids From a Leber's Congenital Amaurosis Patient With Novel
RPE65
Mutations
Frontiers in molecular neuroscience
January 1, 2019
Li G, Gao G, Wang P, Song X, Xu P, Xie B, Zhou T, Pan G, Peng F, Zhang Q,
et al
.
antibody,,, E-cadherin,
Abcam
,
ab76055
,
1:500
KRT7,
GeneTex
,
GTX107343
,
1:500
CD44
,
GeneTex
,
GTX102111
,
1:500
OCT4
,
Bioss
,
bs-0830R
,
1:250
SOX2
,
Abcam
,
ab92494
,
1:100
NANOG,
Abcam
,
ab24624
,
1:1000
SSEA4,
Abcam
,
ab16287
,
1:200
TRA-1-81,Abcam,ab16298,
1:100
TRA-1-60,
Abcam
,
ab16288
,
1:100
PAX6,DSHB,3B5,
1:50
SOX1
,
Abcam
,
ab109290
,
1:200
SIX3
,
Rockland
,
600-401-A26
,
1:500
OTX2,
Abcam
,
ab21990
,
1:500
LHX2
,
Santa Cruz
,
sc-81311
,
1:200
VSX2,
Millipore
,
ab9016
,
1:500
MCM2,
Abcam
,
ab4461
,
1:1000
BRN3,
Santa Cruz
(20)
Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease
Nature Communications
December 1, 2018
Lark L. Coffey et al.
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Anti-Otx1 + Otx2 antibody from Abcam
Supplier Page
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Pricing Info
Product Specs
Company Info
Citations
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